The main lab is the underground location of the Old City Sanctuary where the Sanctuary team do the vast majority of their abnormal medical science research and work. It is located on the lab level - a lower level floor.
History
The area is Helen Magnus's primary lab space. This is a very large open-space two-level circular room full of abnormal enclosures with an automated-assist mechanism ring suspended above. Both levels are comprised of abnormals cells. The bottom level has specified environmental enclosures to match the abnormal it holds. Work tables, chairs, and equipment are constantly added, rearranged, or removed to reflect the current needs of what the space is being used for.
Web Series
| Episode 0x02 - "Webisode 2": to be added | |
| Episode 0x03 - "Webisode 3": to be added | |
| Episode 0x06 - "Webisode 6": to be added | |
| Episode 0x07 - "Webisode 7": to be added |
Season 1
  to be added | |
 to be added | |
| Episode 1x03 - "Fata Morgana": to be added | |
| Episode 1x04 - "Folding Man": to be added | |
| Episode 1x06 - "Nubbins": to be added | |
| Episode 1x08 - "Edward": to be added | |
| Episode 1x10 - "Warriors": to be added |
Season 2
| Episode 2x01 - "End of Nights, Part I": to be added | |
| Episode 2x02 - "End of Nights, Part II": to be added | |
| Episode 2x04 - "Hero": to be added | |
| Episode 2x10 - "Sleepers": to be added |
Season 3
| Episode 3x12 - "Hangover": to be added | |
| Episode 3x20 - "Into the Black": to be added |
Season 4
| Episode 4x02 - "Uprising": to be added | |
| Episode 4x13 - "Sanctuary for None, Part II": to be added |
Notes
- Continuity: The room is referenced as "central lab" by Henry Foss in Episode 1x03 - "Fata Morgana".
- Continuity: The room is referenced as "main lab" by Helen Magnus in Episode 4x13 - "Sanctuary for None, Part II".